The Buffalo Sabres have retired only six numbers since the franchise's inception in 1970.

The first Sabre to have his number retired was Gilbert Perreault (#11) on October 17th, 1990. The combination of center Perreault, left wing Rick Martin and right wing Rene Robert was one of the greatest lines in hockey history and without a doubt the best in Buffalo Sabres' history. The three wore the blue and gold together from 1972 to 1979 and were labeled "The French Connection," a name whose familiarity was helped by the 1971 movie of the same name. The trio was honored as Martin (#7) and Robert (#14) joined Perreault in ceremonies to retire the numbers of Buffalo's famed "French Connection" on November 15th, 1995.

The fourth Sabre to have his number retired was Tim Horton (#2) on January 5th, 1996. The Sabres retired two more numbers during the 2005-06 season. Right winger Danny Gare (#18) was honored on November 22nd, 2005, while Pat LaFontaine's #16 was hoisted to the rafters on March 3rd, 2006.